Connected concepts · Student learning

Foldwords

An evolving ontology and student guide to AlphaFold.

34 terms, explained for students — from amino acids to confidence scores.

Understand AlphaFold, one concept at a time.

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Example & analogy
The same protein from many species, lined up to spot what evolution kept.
Formal description
Positions that mutate together across evolution are likely touching in 3D. AlphaFold reads these patterns as clues.
Why it matters
Not yet documented for this concept.
Common misunderstanding
Not yet documented for this concept. Nicknames are memory aids, not literal definitions.
Connected concepts
- Multiple sequence alignment is related to Coevolution Citation ↗
- Multiple sequence alignment is related to Evoformer Citation ↗
- Multiple sequence alignment is used by Evoformer Citation ↗
- Coevolution is related to Multiple sequence alignment Citation ↗
Sources & citations
- Jumper et al. 2021, Nature (AlphaFold 2 paper) ↗
- EMBL-EBI training: AlphaFold course ↗
Check your understanding
You line up the bead strings from related “The worker machine”s to spot patterns passed down through evolution. What is this collection of clues called?
Explore these connections with the tutor →
See also: