Connected concepts · Student learning

Foldwords

An evolving ontology and student guide to AlphaFold.

34 terms, explained for students — from amino acids to confidence scores.

Understand AlphaFold, one concept at a time.

Follow the concept map →Practice with the quiz →Ask the tutor Build a study plan →Flashcards Nickname quiz Match names ↗Edit glossary Protein models ↗Examples in nature →Model gallery →Explore a protein →Try guided learning →About & sources For teachers

Example & analogy
How confident the model is that two chains really bind together.
Formal description
Interface pTM. Above ~0.8 is a high-confidence interaction prediction.
Why it matters
Not yet documented for this concept.
Common misunderstanding
Not yet documented for this concept. Nicknames are memory aids, not literal definitions.
Connected concepts
- ipTM is related to AlphaFold-Multimer Citation ↗
- ipTM is used to interpret Quaternary structure Citation ↗
- pTM is related to ipTM Citation ↗
- AlphaFold-Multimer is related to ipTM Citation ↗
Sources & citations
- Evans et al. 2021, bioRxiv (AlphaFold-Multimer) ↗
- Abramson et al. 2024, Nature (AlphaFold 3 paper) ↗
Check your understanding
Two “The worker machine”s are predicted to bind. Which score checks confidence where the two partners meet?
Explore these connections with the tutor →
See also: